Cancer jab can eradicate entire tumours in patients, trial shows
GS3Economy · S&T · Environment · Security· Biotechnology & health research· Prelims + Mains·
Why in news
The Institute of Cancer Research (ICR) and Johnson & Johnson announced trial results for a triple-action cancer jab, amivantamab, which showed complete tumor eradication in 15 patients with head and neck or lung cancer.
Background
The amivantamab injection targets EGFR and MET pathways while simultaneously activating the immune system to attack cancer cells. In the trial, the jab shrank tumors in more than a third of patients who had previously failed other treatments.
Facts for Prelims
- S&TAmivantamab: A triple-action cancer jab targeting EGFR and MET pathways.
- FactTrial results showed complete tumor eradication in 15 patients with head and neck or lung cancer.
- BodyInstitute of Cancer Research (ICR): Research body involved in the amivantamab trial.
For Mains
Q. Discuss how advancements in targeted immunotherapy and pathway-specific treatments are reshaping the landscape of oncology and patient outcomes in India.
Dimensions to cover in your answer
- Accessibility gap: High cost of targeted biologics vs. public healthcare affordability
- R&D infrastructure: Need for indigenous clinical trial capabilities for specialized oncology drugs
Keywords: Targeted therapy · Immunotherapy · EGFR pathway · Biotechnology · Oncology
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