SHRI Hospital researcher presents phage therapy to combat antimicrobial resistance in India
GS3Economy · S&T · Environment · Security· Biotechnology & health research· Prelims + Mains·
Biotechnology and public health: Phage therapy as a precision medicine solution for AMR in GS3.
Why in news
Dr. Kalyan Chakravarthy Koganti of SHRI Hospital presented research on phage therapy as a solution to combat antimicrobial resistance in India.
Background
Bacteriophages are viruses that selectively target and kill disease-causing bacteria without harming human cells. SHRI Hospital (Guntur) is collaborating with SRM University and Szeged University to advance the availability of this therapy in India.
Facts for Prelims
- S&TBacteriophages: Viruses that selectively target and kill disease-causing bacteria.
- PostDr. Kalyan Chakravarthy Koganti: Researcher at SHRI Hospital, Guntur.
- FactSHRI Hospital is collaborating with SRM University and Szeged University for phage therapy advancement.
Prelims practice question
With reference to bacteriophages, consider the following statements:
- SHRI Hospital is collaborating with SRM University and Szeged University to advance phage therapy.
- Phage therapy is a method used to treat viral infections by using bacteria.
- Bacteriophages are viruses that kill all types of human cells indiscriminately.
Which of the statements given above is/are correct?
- (a)1 only
- (b)3 only
- (c)1 and 3 only
- (d)1, 2 and 3
Show answer
Answer: (a) 1 only — Statement 1 is correct. Statement 2 is incorrect: Phage therapy uses bacteriophages to target and kill disease-causing bacteria. Statement 3 is incorrect: They selectively target and kill disease-causing bacteria without harming human cells.
For Mains
Q. Discuss the potential of phage therapy in addressing the growing global challenge of antimicrobial resistance (AMR) in healthcare systems.
Dimensions to cover in your answer
- Regulatory hurdle: Lack of standardized clinical protocols and manufacturing guidelines for live viral therapies
- Safety-efficacy trade-off: Balancing the specificity of bacteriophages against potential host immune responses
- Infrastructure gap: Requirement for specialized laboratory facilities to isolate and characterize specific phages
Keywords: antimicrobial resistance · bacteriophages · biotechnology · precision medicine · public health
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