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VOL. I · EST. 11.2025 
SatyaDheesh
सत्याधीश
India's Ground Truth Record
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CDSCO warns against indiscriminate NSAIDs and antibiotics use to prevent renal complications

GS2Polity · Governance · IR· Health policy & public health· Prelims·

Drug regulation and public health: a GS2 case study on antimicrobial resistance and renal health.

Why in news

The Central Drugs Standard Control Organisation (CDSCO) issued a circular warning against the indiscriminate use of NSAIDs and antibiotics to prevent renal complications and antimicrobial resistance.

Background

The CDSCO circular dated September 21, 2026, emphasizes that NSAIDs and antibiotics require prescriptions under Schedule H and H1. Misuse of these drugs is linked to acute kidney injury and chronic kidney disease (CKD), especially in patients with diabetes or hypertension.

Facts for Prelims

  • BodyCDSCO: Central Drugs Standard Control Organisation is the national regulatory body for pharmaceuticals in India.
  • Act / BillSchedule H: Drugs that require a prescription from a Registered Medical Practitioner for sale.
  • Act / BillSchedule H1: A specific category of antibiotics requiring a prescription and carrying a warning for medical advice.
  • FactNSAIDs can reduce blood flow to the kidneys, leading to acute kidney injury or progression of chronic kidney disease.

Prelims practice question

Which schedule specifies a category of antibiotics requiring a prescription and carrying a warning for medical advice?

  1. (a)Schedule M
  2. (b)Schedule G
  3. (c)Schedule X
  4. (d)Schedule H1
Show answer

Answer: (d) Schedule H1 — The CDSCO circular emphasizes that antibiotics in Schedule H1 require a prescription and a warning for medical advice.

For Mains

Q. Discuss the public health implications of antimicrobial resistance and the role of regulatory bodies in curbing the indiscriminate use of over-the-counter medications.

Dimensions to cover in your answer

  • Regulatory enforcement: Challenges in monitoring pharmacy compliance with Schedule H and H1 prescription mandates
  • Clinical stewardship: Need for standardized antimicrobial stewardship protocols to mitigate chronic kidney disease and drug resistance

Keywords: Antimicrobial Resistance · Renal Complications · Schedule H · Pharmacovigilance · Public Health Policy

Read the full news →Report a mistake in this noteSource: The Hindu ↗Also: GS3 · Biotechnology & health research

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